4세 이하 소아에서 과체중이 낙상으로 인한 뇌출혈 발생에 미치는 영향

4세 이하 소아에서 과체중이 낙상으로 인한 뇌출혈 발생에 미치는 영향

Implications of increased weight status for the occurrence of fall-induced intracranial hemorrhage in children aged 4 years or younger

(지상발표):
Release Date :
Jung Heon Kim1, Jae Hyun Kwon2, Jong Seung Lee1, Jeong-Min Ryu1, Kyoung Soo Lim1 , Won Young Kim1
Ulsan University Asan Medical Center Department of emergency medicine1
Ulsan University Asan Medical Center Department of pediatrics2
김중헌1, 권재현2, 이종승1, 류정민1, 임경수1 , 김원영1
울산의대 서울아산 어린이병원 응급의학과1
울산의대 서울아산 어린이병원 소아청소년과2

Abstract

Objectives: To investigate the association between increased weight status (IWS), a weight for age/gender ≥95th percentile, and fall-induced intracranial hemorrhage (ICH) in children aged ≤4 years. Methods: In 7,072 children aged ≤4 years with head injury who visited a tertiary care hospital emergency department in Korea from 2013 through 2015, the presence of fall-induced ICH was reviewed. The association between IWS and ICH was investigated by multivariable logistic regression. We retrospectively validated the Pediatric Emergency Care Applied Research Network rule alone and in combination with IWS for predicting ICH. Results: Of 7,072 children, 547 (7.7%) underwent computed tomography, of whom 451 (6.4%) were enrolled. Of these, 41 (9.1%; estimated event rate, 0.6%) had ICHs, and 26 (5.8%) had IWS. IWS was more common in the children with ICH ( P = 0.023). The association between IWS and ICH remained significant after adjustment (OR, 5.24; 95% CI, 1.49‒18.46; P = 0.010). The validation of the rule in combination with IWS showed no significant increases in the sensitivity (92.7% [95% CI, 80.1%‒98.5%] to 95.7% [95% CI, 83.5%‒99.4%]) and negative predictive value (98.2% [95% CI, 94.7%‒99.4%] to 98.8% [95% CI, 95.4%‒99.8%]). Conclusions: IWS is associated with fall-induced ICH in children aged ≤4 years. Information on weight status could be potentially helpful in predicting ICH in young children with fall-induced head injury.

Keywords: Accidental Falls, Body Weight, Brain Injuries